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[3] CDC data show that the outbreak peaked in September 2019, and declined steadily to a low level through January 2020

The risks of cardiovascular disease and lung disease have not been quantified for e-cigarettes, but are also likely to be substantially less than those from smoking 42

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Total daily nicotine uptake Since humans differ widely with respect to the metabolism of nicotine to cotinine and subsequent elimination of cotinine, the use of cotinine as a marker of nicotine uptake has been questioned