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For the positive mode, 10 mM ammonium formate and 0.1% formic acid were used, while 10 mM ammonium acetate was used for the negative ESI mode

Invest 101 (10), 13081317

As mentioned earlier, SCI triggers various forms of RCD, such as apoptosis, autophagy, pyroptosis, and ferroptosis, due to excessive accumulation of free radicals, mitochondrial dysfunction, glutamate release, and calcium overload

Unlike using the GCI/Vector as a platform, the GSSG ratio of the GCI/ SER3 / SHM2 (41.6 0.2%), GCI/ SER3 / CYS4 (41.0 0.4%), and GCI/ SER3 / SHM2 / CYS4 (40.5 2.0%) at 48 h were higher than that of the GCI/ SER3 (Fig

5b revealed that the gross muscle weight in injured right limb was markedly reduced compared to contralateral healthy left limb, and muscle atrophy was more pronounced in ST and TG groups

For musculoskeletal, joint, and systemic inflammation indications, the subcutaneous injection is the clinically preferred route