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Response rates were correspondingly lower: 66% of Contrave patients achieved 5% weight loss, and 36% reached 10% weight loss

If vitamin B12 absorption disorder is proven, the drug is usually used for life

Morning administration in a fasted state is the most commonly cited timing because endogenous fat mobilisation is naturally elevated after an overnight fast, theoretically amplifying the lipolytic signal from the peptide

(1) Criteria for the use of vitamin B12 (a) approved value in the treatment of pernicious anaemia only (other conditions are very rare in British general practice)

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